Strontium ranelate improves bone microarchitecture in osteoporosis
نویسندگان
چکیده
منابع مشابه
Reference studies for strontium ranelate in the treatment of osteoporosis
Introduction Strontium ranelate is an agent used for the treatment of osteoporosis. It consists of two atoms of stable strontium and an organic part: ranelic acid. Simultaneously, it stimulates the formation of new bone and reduces bone resorption, resulting in a deviation from the balance of bone turnover towards formation. These actions are effected by improving the replication of pre-osteobl...
متن کاملStrontium ranelate in postmenopausal osteoporosis treatment: a critical appraisal
Osteoporosis is a progressive and debilitating disease characterized by a massive bone loss with a deterioration of bone tissues, and a propensity for a fragility fracture. Strontium ranelate is the first antiosteoporotic treatment that has dual mode of action and simultaneously increases bone formation, while decreasing bone resorption, thus rebalancing bone turnover formation. Strontium ranel...
متن کامل[The efficacy of strontium ranelate (Osseor) on fractures in osteoporosis].
The clinical experiences with strontium ranelate (Osseor) in osteoporosis treatment are presented. Strontium ranelate (Osseor) has proven efficacy at the vertebral and nonvertebral levels including patients with osteopenia and osteoporosis regardless of patients age.
متن کاملEffect of strontium ranelate on bone remodeling.
Osteoporosis is a disease in which the microarchitecture of bone tissue deteriorates, with consequent loss of bone mass. Strontium ranelate (SrR) is currently used for treatment of the condition. SrR may have a dual effect: anabolic (stimulating pre-osteoblast replication) and anti-catabolic (reducing osteoclastic activity). However, its mechanism of action has not yet been completely elucidate...
متن کاملStrontium ranelate--does it affect the management of postmenopausal osteoporosis?
This series of articles facilitated by the Cochrane Musculoskeletal Group (CMSG) aims to place the findings of recent Cochrane musculoskeletal reviews in a context immediately relevant to general practitioners. This article considers whether the availability of strontium ranelate affects the management of postmenopausal osteoporosis.
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2009
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/kep274